Test whether aberrations
in the licensing system may provide a selective advantage, through amplification of multiple genomic loci.
As the media "has grown in size and evolved over the years some aberration
shave also crept in, but the good thing is that these aberrations
are being discussed and debated.
Having published volumes on ray geometrical optics and wave diffraction optics, Mahajan, an optical scientist with a California company, continues his series on optical imaging and aberrations
by looking at wavefront analysis, an integral part of optical design, fabrication, and testing.
First, the entire genome was divided into 1-Mb windows, similar to the analysis of copy number aberrations
in the tumor tissues.
Key Words: Cytogenetcis, Myeloma, FISH, Chromosomal aberrations
: The two types of chromatic aberration
are axial chromatic aberration
, where the focal point position on the optical axis varies according to the wavelength, and chromatic difference or magnification, where the image magnification in peripheral areas varies according to the wavelength.
Earlier studies have also demonstrated that automobile exhaust can induce gene mutations, chromosomal aberrations
, sister chromatid exchanges, micronuclei and cell transformation (5-7).
Two short communications at the end of the volume investigate excimer laser surgery and PRK induced negative spherical aberrations
For simultaneous monitoring of all 8 data streams, we monitored separate aberrations
as above and generated alerts based on the first occurrence of any aberration
(M1), 2 simultaneous aberrations
(M2), the first occurrence of 3 simultaneous aberrations
(M3), any 2 aberrations
within a 2-week period (M4), and any 3 aberrations
within a 2-week period (M5).
The tests confirmed the oral LD50 is greater than 2000 mg/kg, there was no oral toxicity in rats receiving 1000 mg/kg/day for 4 weeks, is not mutagenic to the bacteria used, did not induce either structural or numerical chromosome aberrations
, did not induce micronuclei in bone marrow cells of mice, had no skin sensitizing potential in the guinea pig maximization test, and had no toxic effects on immuno-toxicological parameters tested at 1000 mg/kg body weight/day for 4 weeks.
Some fear them as barbaric aberrations
of humanity; others see them as the next step in human evolution.
The author's research focuses primarily on neurological dysfunctions caused by small changes in a person's brain, These aberrations
, in turn, can indicate how the normal brain functions.