is a major depressive disorder characterized by a distinct combination of symptoms that include mood swings, carbohydrate cravings, weight gain, rejection sensitivity and lethargy.
is usually less severe than melancholia.
Greater efficacy from curcumin treatment was identified in a subgroup of individuals with atypical depression
Specifically, clinical trials of longer duration are warranted to assess the effect and efficacy of curcumin over a longer period of time, varied dosing regimes to understand the optimal dose, and larger study groups to elicit understanding of differences in responses in different categories of MDD such as atypical depression
and in conjunction with different antidepressant therapies.
67] Atypical depression
is characterised by mood reactivity, significantly decreased energy or leaden feelings in the limbs (leaden paralysis), heightened sensitivity to interpersonal rejection, and a reversal of neurovegetative symptoms (increased sleep and appetite).
In enduring stressful conditions, we may have adapted evolutionarily to suppress our cortisol levels because higher and more prolonged levels of cortisol in the bloodstream can lead to negative health consequences, such as autoimmune disorders, lowered immunity, arthritis and atypical depression
More specifically it has been reported that, obesity is the clinical manifestation of a subtype of depression similar to that of atypical depression
008) while changes in atypical depression
scores were significantly related to allergy-specific IgE positivity (P = .