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The microparticle delivery has early promising results in the ongoing Resten-MP APRAISAL clinical trial that we took over from AVI.
In addition to the primary data in these studies, AVI scientists intentionally triggered the opposite effect by inducing another altered splice form of CTLA-4 by employing a different antisense sequence.
AVI is conducting this study in collaboration with Harvard Clinical Research Institute (HCRI), an internationally recognized organization specializing in the management of coronary artery disease and stents.
In addition, Eleos is making an upfront payment of $500,000 to AVI.