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There is only one logical explanation for this finding, sauna therapy must act to produce a large increase in the second enzyme in the pathway, PTPS, as well, leading to increased metabolism of the dihydroneopterin triphosphate in the BH4 biosynthetic pathway and therefore decreased generation of neopterin.
Pyridoxal (PL) kinase encoded in Arabidopsis thaliana (SOS4) is a key enzyme involved in the biosynthetic pathway leading to Pyridoxal 5'-P (PLP).
Important follow-on work provided the answer to an otherwise puzzling question: why VP and hereditary coproporphyria (HCP) are associated with acute elevations in [delta]-aminolaevulinic acid (ALA) and porphobilinogen (PBG) and thus the acute attack, whereas porphyria cutanea tarda (PCT) is not, even though the enzymatic defect in PCT occurs more proximally in the haem biosynthetic pathway (Fig.
Focus on unstudied groups of organisms, enzymes, and habitats provides access to novel biosynthetic pathways and chemical scaffolds.
Reduced root development in glyphosate-resistant soybean may be explained by the fact that the incorporation of the CP4-EPSPS gene in this plant species leads to drastic changes in the biosynthetic pathway of aromatic amino acids, reducing their levels (BRENBROOK, 2001).
A typical metabolic engineering workflow involves the recognition of an interesting product and the identification of the biosynthetic pathway leading to that product.
The objective of the study is to clone and characterize one or more key polyketide synthase (PKS) genes associated with the production of solanapyrones in Ascochyta rabiei, to establish their role in the solanapyrone biosynthetic pathway and their effect on pathogenicity of the fungus.
Thus, direct optimization of the rubber biosynthetic pathway seems to present the most likely route to achieve significant gains in latex and rubber yield.
Commonwealth Scientific & Industrial Research Organisation (Campbell, Australia), The Austrailian National University (Acton, Australia) and Biogemma SAS (Paris, France) have patente a nucleic acid sequence encoding an enzyme of the starch biosynthetic pathway in a cereal plant, wherein the enzyme is selected from the group consisting of starch branching enzyme I, starch branching enzyme II, starch soluble synthase I, and debranching enzyme, with the provisio that the enzyme is not soluble starch synthase I of rice, or starch branching enzyme I of rice or maize.
The heme biosynthetic pathway is a metabolic target for two common toxins - lead and ethanol.
This paper employed the biosynthetic pathway leading to the synthesis of the amino acid lysine to illustrate the software and information available on the internet, concerning protein and gene sequences.