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These designations were granted because Chagas disease is a rare disease, and until now, there were no approved drugs for Chagas disease in the United States.
Preventing and controlling congenital Chagas disease is a serious public health issue; the screening of mothers at risk for transmitting T.
The literature shows that there is sufficient evidence to recommend etiological treatment in the acute stage of Chagas disease (congenital- or vector-borne), as well as in any stage in children aged [less than or equal to]19 years (5, 6).
Migration from rural to urban areas in Brazil and other Latin American countries has particularly increased the probability of individuals with Chagas disease to contract HIV.
A battery of noninvasive tests was performed in order to assess for common cardiac manifestations of Chagas disease, including, but not limited to, left ventricular dilatation and dysfunction, wall motion abnormalities, aneurysms, diastolic dysfunction, pathologic bradyarrhythmias and tachyarrhythmias, and ischemic heart disease.
In the 20th century it was one of the areas that had the highest rates of the Chagas disease, with the triatomine insects often being found in people's households.
Experimental benznidazole treatment of Trypanosoma cruzi II strains isolated from children of the Jequitinhonha Valley, Minas Gerais, Brazil, with Chagas disease.
The report provides a snapshot of the global therapeutic landscape of Chagas Disease (American Trypanosomiasis)
In August 2015, the Food and Drug Administration determined that Chagas Disease was added to the list of designated tropical diseases whose product applications may result in the award of a PRV.
Research priorities for Chagas disease, human African trypanosomiasis and leishmaniasis.
Therefore DhL and Hln may offer an interesting option for the treatment of Chagas disease, alone or in combination with conventional drugs.