Mutation analysis for a family affected with Charcot-Marie-Tooth disease
type 4C (in Chinese).
The study of the genealogy of the patient, the phenotype features, and the NCV and EMG findings must be included as valuable tools in the clinical approach of the patient with Charcot-Marie-Tooth disease
, recessive axonal type.
A review of the Charcot-Marie-Tooth Disease
products under development by companies and universities/research institutes based on information derived from company and industry-specific sources
Table: Genetic classification of Charcot-Marie-Tooth disease
Demyelinating and axonal features of Charcot-Marie-Tooth disease
with mutations of myelin-related proteins (PMP22, MPZ and Cx32): a dinicopathological study of 205 Japanese patients.
Familial trigeminal neuralgia in Charcot-Marie-Tooth disease
is one of the most common inherited neurological disorders, affecting one in 2,500 people in the United States.
According to Pharnext this round of fundraising will enable the company to consider launching the first-in-man clinical trials of its Pleodrug in the treatment of Charcot-Marie-Tooth disease
before the end of 2010.
Restricted ankle dorsiflexion range--or ankle equinus--is a common impairment in children and adolescents with Charcot-Marie-Tooth disease
(Burns et al 2009a).
According to a study published in the Lancet Journal, Charcot-Marie-Tooth disease
type 1A (CMT1A) is a hereditary peripheral neuropathy that affects roughly one in 5000 births.
Among the categories covered are: spinal muscular atrophies, poliomyelitis, Charcot-Marie-Tooth disease
and related disorders, vasculitic neuropathies, neuropathies associated with infections, muscular dystrophies, congenital myopathies, myotonic dystrophies, and toxic myopathies, among others.
An example of this benefit is that a primary demyelinating characterization greatly narrows the list of possible causes (eg, Guillain-Barre syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, Charcot-Marie-Tooth disease