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Mutation
(redirected from Chromosomal gain)

    Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.03 sec.

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.
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For solid tumors, at least, this is mainly attributed to the introduction of techniques, such as comparative genomic hybridization (CGH),1 which for the first time, enabled the analysis of chromosomal gains and losses without the necessity of preparing metaphase spreads from the specimen to be analyzed.
An Integrative Approach for Analyzing the Interplay of Genetic and ... by Artur Muradyan and Vivien Boldt and Anne Steininger and Stephanie Stabentheiner and Katrin Tebel and / Archives of Pathology & Laboratory Medicine
Each chromosomal gain or loss, genetic abnormality, or other mutagenic event contributes to the full context of a disease pathway, regardless of whether it's the first, second, or twentieth cumulative hit.
Roche NimbleGen CGH Microarrays Further Our Understanding of ... by Business Wire
Agilent originally launched its breakthrough oligonucleotide (oligo) aCGH platform in January 2005, with a microarray for genome-wide scanning of chromosomal gains and losses on a single chip.
TRADE NEWS: Agilent Technologies Introduces HD-CGH Custom Microarrays ... by Business Wire
 
 
 
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