coagulation

(redirected from Clotting factors)
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Importantly, the difference in the duration of activity of rFVIIIFc and rFIXFc was expected and consistent with the differences between the natural clotting factors that these products augment.
For more than two decades, many research teams, including at CHOP, have investigated gene therapy strategies that deliver DNA sequences carrying genetic code to produce clotting factor in patients.
1],[2]] Due to the deficiency in blood clotting factors induced by warfarin treatment, patients are at increased risk of bleeding, especially if undergoing an urgent surgery or invasive procedure.
rFVIIa is an activated form of factor VII and can bypass the need for factor VIII or IX in people with hemophilia who have developed inhibitors to clotting factor concentrates to restore factor VIII or IX.
The bill creates "The Bleeding Disorders Treatment Fund" by taxing manufacturers of blood clotting factor 6% and specialty pharmacies at 2% of their sales of blood clotting factor.
In a study of 56 HIV-antibody-positive hemophiliacs who received non-heat-treated clotting factors, all but one had HIV DNA in their blood when tested with the extremely sensitive polymerase chain reaction test -- indicating they are indeed infected with the virus and at high risk of contracting AIDS.
Gili Hart, Director of Pre-Clinical Affairs at PROLOR and head of the company's long-acting clotting factors program.
Whereas other clotting factors rely upon proteolytic activation by blood-borne enzymes, tissue factor triggers coagulation in response to tissue damage.
plasma centers and 8 German plasma centers as well as significant plasma procurement programs in Europe and the USA, the supply from BCA will be used to produce ZLB Behring's immunoglobulin products, plasma-derived clotting factors, Alpha-1 proteinase inhibitor, and critical care and wound-healing therapies.
Gili Hart will present data on its long-acting clotting factors in preclinical development for the treatment of hemophilia at the European Association for Haemophilia and Allied Disorders (EAHAD) 5th Annual Congress.
Factor IX levels in excess of 3 percent of normal levels are expected to substantially reduce spontaneous bleeding episodes and reduce or eliminate patients' dependence on repeated injections of clotting factors.