depressant

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Likewise, alcohol and other CNS depressant drugs may have additive effects on psychomotor performance when used with zolpidem.
With regard to CNS depressants, five subjects (38%) reported using alcohol, and one reported taking clonazepam while intoxicated with GHB.
CNS Depressants Concurrent use of oxymorphone hydrochloride extended-release tablets and other CNS depressants including sedatives, hypnotics, tranquilizers, general anesthetics, phenothiazines, other opioids, and alcohol can increase the risk of respiratory depression, hypotension, profound sedation, or coma.
ZUTRIPRO([TM]) Oral Solution should not be taken with alcohol or other CNS depressants.
Avoid use of Karbinal ER with alcohol and CNS depressants (hypnotics, sedatives, tranquilizers, etc.
Concurrent use of EXALGO with CNS depressants, including alcohol, increases risk of respiratory depression, hypotension, and profound sedation, potentially resulting in coma or death.
Hydrocodone may impair mental and/or physical abilities when ingested with alcohol and other CNS depressants.
Dose reduction of CNS depressants, ZUBSOLV sublingual tablet, or both should be considered in situations of concomitant prescription