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Related to Corneocyte: stratum corneum
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The stratum corneum has been described as a 'brick wall' (Cork and Danby 2009 p872-877) where the 'bricks' are corneocytes.
If larger than a few nanometers, penetration via the intercellular lipids or through keratinized corneocytes may not be possible and while partition into the follicle is theoretically feasible, it is occurring under specific facilitating conditions or with the use of exceptional materials.
Schmuth M, Gruber R, Ellias PM, Williams ML: Ichthyoses update: towards a function driven model of pathogenesis of the disorder of cornification and the role of corneocyte proteins in these disorders.
The corneocytes are expanded in soft cerumen, but not in hard cerumen.
When discussing with parents how the protective barrier functions considering the strateum corneum as a brick wall with the corneocytes as bricks and the lipids as cement can be a useful analogy to illustrate how the decreased barrier function of the corneum stratum makes an infant's skin more permeable and inclined to dryness (Elias, 1996).
In contrast, a lotion with a low amount of glycerin and a neutral emulsifier was significantly less effective at preventing dryness, surface corneocyte damage and dehydration.
Elias, a dermatology professor at the University of California, San Francisco, has published various papers during his 30-year career and is currently researching corneocyte structural proteins and their role in the permeability barrier function.
Our objective was the construction of a three-dimensional model of the stratum corneum, corneocyte arrangements and lipid pathlengths," said Dr.
However, it is believed that they can deliver the cosmetic active by adhering to the corneocyte through diffusion as a result of fusion of bilayers of liposomes with the proteins and lipids of the stratum corneum.
Naoko Ota, Pola Chemical, suggested researchers can identify consumers with sensitive skin through corneocyte measurements.