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dna
(redirected from DNA ligase)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia 0.01 sec.

DNA n. scientifically, deoxyribonucleic acid, a chromonal double chain (the famous "double helix") in the nucleus of each living cell the combination of which determines each individual's hereditary characteristics. In law, the importance is the discovery that each person's DNA is different and is found in each living cell, so a hair, blood, skin or any part of the body can be used to identify and distinguish an individual from all other people. DNA testing can result in proof of one's involvement or lack of involvement in a crime scene. While recent DNA tests have proved a convicted killer on death row did not commit a crime and resulted in his release, current debate concerns whether DNA evidence is scientifically certain enough to be admitted in trials. The trend is strongly in favor of admission.


dna noun authentication, certification, confirmation of identity, proof of identity, scientific evidence, scientific means of designation, scientific means of identity, scientific means to distinguish a person, scientific method to reveal identity, substantiation, validation of identity, verification of identity, deoxyribonucleic acid
Associated concepts: appeal of a case, DNA fingerprint, DNA polymerase, forensics, overturning a case, reversal of a case


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In the single-strand break repair pathway, hPNKP acts in concert with XRCC1, DNA polymerase h, and DNA ligase III (16?
It forms repair complexes with poly(ADP-ribose) polymerase (22, 23), DNA polymerase- (24, 25), DNA ligase III (26), human apurinic/apyrimidinic endonuclease (27), and proliferating cell nuclear antigen at DNA replication foci to facilitate SSB repair during S phase (28).
A total of 250 ng genomic DNA was completely digested with 3 units of MseI (BioLabs) in a 25 [micro]L volume, and then 15 [micro]L of digested DNA was ligated to MseI AFLP adaptor (5'-GACGATGAGTCCTGAG-3'/5'-TACTCAGGACTCAT-3') using 1 unit of T4 DNA ligase (BioLabs) in a 30 [micro]L volume at 20[degrees]C for 3 h.
 
 
 
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