14) These foam cells
then die, creating debris that fill the inflamed tissue and perpetuate even more inflammation.
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell
transformation in human THP-1 monocyte/ macrophages.
It has been shown that high density lipoprotein (HDL) cholesterol and its most abundant protein constituent, apolipoprotein A-I (ApoA-I), can promote the efflux of cholesterol from foam cells
of the artery wall and mediate the transport of cholesterol to the liver for catabolism (Fielding and Fielding 1995; Panagotopulos et al.
Smaller, denser LDLs are associated with increased development of atherosclerosis and foam cells
1,25 (OH)2 vitamin D inhibits foam cell
formation and suppresses macrophage cholesterol uptake in patients with type 2 diabetes mellitus.
This may be due to the fine structure nature of the foam cells
formed as a result of the oleochemical activities of castor oil in the mixture.
with vacuolated cytoplasm may be present, and they often have pigmented cytoplasmic granules containing hemosiderin.
The foam cells
are larger than desired, cell density is lower than optimum, and cell-distribution is very non-uniform.
Macrophages play a key role in atherogenesis by releasing proinflammatory cytokines and forming foam cells
in subendothelial lesions.
Shear reduction: The mattress uses a combination of a sheath liner and a unique top surface featuring 800 individual responsive foam cells
designed to move with the patient, reducing friction on the patient's skin.
The histogenesis and classification of fibrohistiocytic lesions involving bone and containing an admixture of fibrous tissue, foam cells
, and giant cells are confusing and include several overlapping entities, such as metaphyseal fibrous defect, nonossifying fibroma, fibrous cortical defect, fibroxanthoma, and benign fibrous histiocytoma (BFH) of bone.
The earliest lesions of atherogenesis consist of arterial intimal accumulations of foam cells
(primarily lipid-laden macrophages) and T lymphocytes intermixed with smooth muscle cells (7).