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phase
(redirected from G1 phase)

   Also found in: Dictionary/thesaurus, Medical, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.


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CXS299 selectively blocks tumor cells in G1 phase of the cell cycle, which makes the agent unique, more potent and less prone to cross-resistance compared to approved platinum therapies.
In particular, CLT inhibits translation initiation and thereby accumulation of proteins such as cyclin D1, E and A, called G1 cyclins, that promote cell growth in the G1 phase of the cell cycle.
 
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