The researchers found that the mice with GM-CSF
had a better chance of survival than the other mice.
On comparing the patients to the control group by serum levels of GM-CSF
, we noted considerably lower GM-CSF
levels in the sera of vitiligo patients; the mean [+ or -] SD was 33.
Effects of recombinant chicken GM-CSF
and IL-4 collectively and individually on cell segregation were recorded by observing cell morphology, clustering, none clustering and maturation of cell.
After a 24 h incubation period, GM-CSF
induced no increase in CCR3 expression on eosinophils and was not modulated by co-incubation with different concentrations (0.
6] Nonstandard abbreviations: MIA, multiplex immunoassay; SGBS, Simpson-Golabi Behmel syndrome; RBP-4, retinol binding protein 4; PAI-1, plasminogen activator inhibitor 1; SAA-1, serum amyloid A1; TIMP-1, tissue inhibitor of metalloproteinase 1; HPE, high-performance ELISA; LLOD, lower limit of detection; LLOQ, lower limit of quantitation; GM-CSF
, granulocyte-macrophage colony-stimulating factor; HGF, hepatocyte growth factor; IL, interleukin; MCP-1, monocyte chemoattractant protein 1; MIF, macrophage migration inhibitory factor; NGF, nerve growth factor; MIP-1[alpha], macrophage inflammatory protein 1[alpha]; TNF-[alpha], tumor necrosis factor [alpha].
mouthwashes have been shown to cause marked alleviation of existing oral mucositis in several studies without detectable systemic accumulation of GM-CSF
upon systemic neutrophil count.
Several studies have demonstrated treatment efficacy in the use of subcutaneous (49,50) or aerosolized (51) GM-CSF
for patients with idiopathic PAP.
The researchers confirmed that GM-CSF
mouthwash conferred no benefit to oral mucositis despite promising results in preclinical and phase I trials and further recommended that other agents are similarly scrutinised using an RCT design.
The association between infection and GM-CSF
concentrations persisted even after the investigators controlled for center, tobacco use, and bacterial vaginosis, said Dr.
Methylcellulose semi-solid media (Stem Cell Technologies, Inc, Vancouver, BC) containing the following growth factors: stem cell factor (50 ng/mL), GM-CSF
(10 ng/mL), Interleukin-3 (10 ng/mL), and Erythropoietin (3 U/mL).
When given to chronically HIV-infected patients during an STI, GM-CSF
blunted viral rebound and substantially prevented decreases in CD4 T cells in the absence of antiretroviral treatment.
5 when a research group led by assistant professor Kenzaburo Tani removed the man's right kidney and then introduced immunity-enhancing GM-CSF
genes into cancer cells taken from the diseased kidney.