knockdown

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Related to Gene knockdown: Gene knockout

knockdown

verb accost, assault, attack, batter, be reckless in harming a person, beat, besiege, damage, deal a blow, harm, hit, hurt, inflict harm, inflict injury, injure, shruck off
Associated concepts: assault, battery, dart out case, hit and run
References in periodicals archive ?
Our results showed that the gene knockdown efficiency and stability of the gene silencing effects were increased when the pooled siRNA fragments were used.
Co-transfection of the two different siRNA sequences targeting different sequences of CYP19 gene showed a synergistic effect resulting in higher gene knockdown achieved in comparison to individual transfection of the two siRNA (p<0.
Successful gene knockdown with RNAi was also demonstrated with the caspase 3 activity assay, which showed the gene-specific phenotypic knockdown of acasp.
The same effectiveness of gene knockdown has been observed for inhibiting in vitro the synthesis of the Spike (S) protein from the recently emerged SARS-associated coronavirus (SARS-CoV), the etiologic agent of the severe acute respiratory syndrome (52,53).
She will also discuss strategies for targeted gene knockdown that use RNA aptamers or antibodies for selectively delivering siRNAs into cells outside the liver.
Arrowhead Research Corporation (NASDAQ:ARWR), a targeted therapeutics company, today announced the publication of data demonstrating that high level target gene knockdown with low doses of cholesterol-siRNA is possible in non-human primates using the company's Dynamic Polyconjugate (DPC) delivery system and a novel co-injection strategy.
The kit has multiple advantages for RNAi applications and compatible with siRNA complexing and administration to achieve sustained gene knockdown (gene silencing via in vivo mRNA knockdown) after a single injection.