in the human prostate: A new therapeutic target?
of Cajal are unique pacemaker cells interposed between the autonomic nervous system and the muscular wall of the GI tract and are responsible for coordinated peristalsis.
Pyeloureteric peristalsis: role of atypical smooth muscle cells and interstitial cells
of Cajal-like cells as pacemakers.
It is proposed that the origin of GISTs is from the interstitial cells
of Cajal (ICC) given their CD117 and CD34 expression and histologic similarities to this cell.
The interstitial cells
of Cajal (ICC) are mesenchymal cells arranged in a characteristic manner in close relation to the nerves and smooth muscle cells in the outer muscular coat of the GI tract4.
In one case, myenteric hypoganglionosis and reduction in numbers of interstitial cells
of Cajal were observed.
It is now believed that GISTs arise from precursor GI cells that differentiate into the interstitial cells
Louis, MO) to separate interstitial cells
and seminiferous tubules.
So there is the possibility of injury, loss of interstitial cells
and Sertoli in this way.
Taken together, EP inhibits myofibroblast expansion and cytoskeletal proteins expression, accompany by the capacity of release collagen secretion, suggest that EP may disturb the process of renal interstitial cells
dedifferentiation into myofibroblasts.
The sections of the uninvolved gallbladder wall did not show CD117-positive interstitial cells
A key pathogenic role in this specific form of primary pulmonary hypertension is played by pulmonary interstitial cells