Coronary arteriography, performed via the right femoral artery, showed proximal total occlusion of the left anterior descending coronary artery
, diffuse disease of the left circumflex coronary artery with a totally occluded first obtuse marginal branch and 90% narrowing of the third obtuse marginal branch, and diffuse disease of the right coronary artery with a long 80% to 90% narrowing in its mid segment.
Patients with isolated left anterior descending coronary artery
disease undergoing nonemergent revascularization may be successfully treated currently with angioplasty (often with the concomitant use of intracoronary stent), conventional CABG, or the new and evolving technique of MIDCAB.
The following day the patient underwent three-vessel coronary arterial bypass grafting using the left internal mammary artery to the left anterior descending coronary artery
and saphenous vein grafts to the first obtuse marginal branch of the left circumflex coronary artery and the posterior descending branch of the right coronary artery.
Overall, 69% of enrollees had multivessel disease, and one-half of those had involvement of the left anterior descending coronary artery
A group of 33 dogs undergoing openchest left anterior descending coronary artery
(LAD) ligation causing prolonged ischemia were imaged with quantitative positron emission tomography (PET) using 2-[18F]fluoro-2-deoxy-D-glucose (18FDG) to measure regional glucose metabolic utilization (rGMU) and [11C]acetate to measure regional monoexponential washout rate constant (Kmono) for oxidative metabolism in nonrisk and ischemic-risk myocardium.
Coronary angiogram was performed, which revealed widespread thrombus in the mid and distal left anterior descending coronary artery
Dual left anterior descending coronary artery
is defined as the presence of two LADs within the anterior inter-ventricular sulcus: a short LAD that courses and terminates low in the AIVS, and a long LAD that originates from either the LAD proper or the right coronary artery, then enters the distal AIVS and courses to the apex.
He had a history of systemic hypertension, hyperlipidemia, and coronary artery disease, with percutaneous coronary intervention and a stent to his left anterior descending coronary artery
placed 3 years earlier.
These measures were as follows: (a) selecting animals showing ST segment elevation; (b) inducing an extensive area of myocardium by proximally occluding the left anterior descending coronary artery
, which perfuses 25-40%  of the ventricular myocardium; (c) restoring coronary flow for more rapid and complete washout of CK; (d) sampling blood frequently for CK analysis; (e) using sensitive assays to detect mitochondrial and cytosolic CK; (fl assaying for mitochondrial CK independent of enzyme activity; (g) keeping the animal alive for 48 h after occlusion to optimize detection of manifestations of irreversible injury by light and electron microscopic analysis.