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Mutation |
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MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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2003) presented the results of an investigation of more than 16,000 genes for loss-of-function phenotypes in C. By yielding direct and highly predictive insights into the cellular functions and loss-of-function phenotypes of analyzed genes, this RNAi-based approach will enable Merck to efficiently select targets with higher confidence for driving their drug development programs. The method of identification, based on detailed analysis of RNAi-induced loss-of-function phenotypes in living human cells, conveys upon these targets a significantly stronger patho-physiological relevance than that typically seen for targets identified by less probative "first-wave" genomics methodologies of recent years. |
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Loss-of-function
