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| Outbreaks of disease suspected of being due to human monkeypox virus infection in the Democratic Republic of Congo in 2001. In two additional primate trials, SIGA-246 afforded complete protection against the monkeypox virus, a closely related disease that is even more virulent in that species. This was the first instance of human monkeypox virus (MPXV) infection detected outside its endemic range in Africa (3). |
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