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Eli Lilly and Company sponsored the Multiple Outcomes of Raloxifene Evaluation (MORE) Trial.
The Multiple Outcomes of Raloxifene Evaluation (MORE) trial was originally designed to test the effects of 60 mg and 120 mg of raloxifene--a selective estrogen-receptor modulator marketed as Evista by Eli Lilly and Co.
Interest in the drug's cardioprotective potential was sparked in large part by a posthoc analysis of the landmark Multiple Outcomes of Raloxifene Evaluation (MORE) trial, which showed a 40% reduction in cardiovascular events with raloxifene, compared with placebo, in the subset of participants at increased cardiovascular risk.
Using original data from the Multiple Outcomes of Raloxifene Evaluation, the authors present a secondary analysis of this randomized trial to evaluate its effect on cardiovascular events.

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