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Uterine safety during treatment with Evista has already been established through a number of studies, including the four-year Multiple Outcomes of Raloxifene Evaluation (MORE) trial, with more than 6,000 postmenopausal women with a uterus.
Two sequential trials have found that raloxifene protects against breast cancer: the Continuing Outcomes Relevant to Evista (CORE) trial and the Multiple Outcomes of Raloxifene Evaluation (MORE) trial.
In the Multiple Outcomes of Raloxifene Evaluation (MORE) study involving more than 7,700 women, researchers found that Evista reduces the risk of new spinal fractures by 55 percent in the first three years of treatment in women who had not yet suffered a fracture.
For example, the data on raloxifene from the Multiple Outcomes of Raloxifene Evaluation (MORE) study [JAMA.
The new four-year data are derived from a retrospective analysis from the Multiple Outcomes of Raloxifene Evaluation (MORE) Study, an evidence-based osteoporosis treatment study involving 7,705 postmenopausal women with osteoporosis.

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