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mutate |
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The failure to show mutator phenotypes in Beijing/W strains suggests that this role may have been transient (10,11). Most microorganisms are willing hybridizers and mutators, easily adapting to changing circumstances. The cell defects - caused by any number of factors, including heredity, viruses, radiation, environment, lifestyle - spell trouble when occurring in three categories of genes: oncogenes, which turn on cell division; tumor-suppressor genes, which switch off the process; and mutator genes, which, when flawed, increase the rates of mutation in the other two groups. |
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