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Environmentally responsive mutator systems: toward a unifying perspective.
Sometime long in the past, Zapotec farmers must have selected kernels for reseeding that contained an inhibitor of the mutator transposon, whose effect is thus countered as long as the maize is exclusively inbred, If crossed with other races, however, the mutator transposon can escape to other breeds and act like a genetic time bomb.
Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype.
Isolation and characterization of ten mutator alleles of the mitochondrial DNA polymerase-encoding MIP1 gene from Saccharomyces cerevisiae.
March 14 /PRNewswire/ -- The Immune Response Corporation (Nasdaq: IMNR) announced today that the United States Patent Office has issued a patent on its licensed technology entitled "Methods of Identifying Lymphocytes with Mutator Phenotypes.
Contingency loci, mutator alleles, and their interactions.
Genetic instability and the mutator phenotype: studies in ulcerative colitis.
The failure to show mutator phenotypes in Beijing/W strains suggests that this role may have been transient (10,11).
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?
Mutations in putative mutator genes have been found in Beijing genotypes, which suggests adaptability (5), but no increase in the rate of acquisition of resistance to rifampicin was found in in vitro studies (35).