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Setting Standard Criteria to Define Neuropathic Pain Phenotypes
The capsaicin 8% patch is approved by the European Medicines Agency for the treatment of peripheral neuropathic pain in adults either alone or in combination with other medicinal products for pain.
Neuropathic pain is not a single disease, but a syndrome caused by a range of different diseases and lesions, which has a considerable impact on the quality of life (QoL).
The data from these studies will inform the design of a subsequent Phase 2 proof of concept study in neuropathic pain.
Gabapentinoids, which are now considered to be first-line treatment for post-SCI neuropathic pain, mimic the neurotransmitter GABA and show indirect interaction with the GABA receptor.
According to IMS Health Disease Insights 2014, sales of the key products to treat neuropathic pain in the US alone were approximately US$4 billion in 2013.
Neuropathic pain, a form of chronic pain that occurs in conjunction with injury to-or dysfunction of-the nervous system, can be debilitating and difficult to treat, and the medical community is eager to find better methods to minimize what can be a serious condition.
A snapshot of the global therapeutic scenario for Diabetic Neuropathic Pain.
Dr Chen and colleagues examined the effects of exercise on neuropathic pain induced by sciatic nerve injury in rats.
Neuropathic pain is caused by damage to, malfunction of, or pathology affecting either the peripheral nervous system or the central nervous system - originating in the brain or spinal cord.
The study shows that neuropathic pain is a major contributor to chronic lower back pain in the region which means it is essential that doctors are diagnosing the condition correctly.
Hochman, a rheumatologist at Women's College Hospital in Toronto, explained that current theories about pain point to the possible development of neuropathic pain as a result of the chronic, nociceptive stimulation associated with osteoarthritis.