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Treatment is indicated in patients with Pagets disease of bone
Presumably due to the effects of FOSAMAX on increasing bone mineral, small, asymptomatic decreases in serum calcium and phosphate may occur, especially in patients with Pagets disease, in whom the pretreatment rate of bone turnover may be greatly elevated.
GBI Researchs analysis shows that the overall global bone metabolism therapeutics market for the four indications (which includes osteoporosis, Pagets disease of bone, hyperparathyroidism and bone metastases) was valued at $15 billion in 2010, growing from $10.