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Related to Plasminogen activator inhibitor: tissue plasminogen activator, SERPINE1, endothelial plasminogen activator inhibitor
See: deterrent
References in periodicals archive ?
ELISA systems for active and total plasminogen activator inhibitor 1 (PAI-1) antigen.
Kinetic analysis of the interactions between plasminogen activator inhibitor 1 and both urokinase and tissue plasminogen activator.
Randomized adjuvant chemotherapy trial in high-risk node-negative breast cancer patients identified by urokinase-type plasminogen activator and plasminogen activator inhibitor type 1.
The pathogenesis of accelerated fibrinolysis in liver cirrhosis: a critical role for tissue plasminogen activator inhibitor.
uPA activity is rapidly neutralized by specific high-affinity plasminogen activator inhibitors (PAIs) (6).
Correlation between blood fibrinolytic activity, plasminogen activator inhibitor level, plasma insulin level and relative body weight in normal and obese subjects.
The fibrinolytic activity of blood depends on the balance between the circulating concentrations of tissue-type plasminogen activator (t-PA) (4) and plasminogen activator inhibitor type 1 (PAI-1), which are both secreted by endothelial cells [2].
In addition to XR9576 and XR5000, Xenova is also currently undertaking cancer research projects targeting MRP-related multi-drug resistance, next generation topoisomerase inhibitors, the potential of P-gp in oral drug delivery and plasminogen activator inhibitor (PAI-1).
Measurement of the protein components of the urokinase system in tumor extracts reveals that high concentrations of uPA, uPAR, and plasminogen activator inhibitor type 1 (PAI-1) are associated with shorter survival of breast cancer patients [16-23], and therefore may be used as prognostic markers.

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