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Serotonergic neurons from the dorsal and medial raphe nuclei project to hypothalamus, activating the hypothalamo-pituitary-adenocortical (HPA) and the hypothalamo-pituitary-gonadal (HPG) axes in the rat (Fuller 1996; Jorgensen et al. The raphe nuclei were included in the area of hemorrhage bilaterally, which is consistent with the observed fluctuations in level of arousal. Fibers emanate from clusters of serotonin-producing nerve cells -- primarily regions called the raphe nuclei -- along the mid-line of the brain stem. |
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