Life-threatening respiratory depression
is more likely to occur in these patients, as they may have altered pharmacokinetics or altered clearance compared with younger, healthier patients.
Urinary retention and respiratory depression
were not observed in any patient.
Cautiously adjust the dose of Lazanda in patients with chronic obstructive pulmonary disease or preexisting medical conditions predisposing them to respiratory depression
Key Words: intrathecal, morphine, audit, elderly, respiratory depression
Possible adverse effects are numerous, and may include nausea, vomiting, constipation, sedation, convulsions, respiratory depression
, dysphoria, urinary retention, rash, hives, pruritus, bradycardia, and hypotension.
Galleon estimates there are 23 million surgeries performed every year which require anesthesia and pain control, with an estimated 35-40% of those being done in patients at higher risk for respiratory depression
Serious adverse reactions may occur with MorphaBond which include addiction, abuse, and misuse, life-threatening respiratory depression
especially in elderly, cachectic, and debilitated patients.
This merger brings together a series of unique drug products that in preclinical animal models and early clinical studies have shown efficacy in preventing or reversing drug-induced respiratory depression
and in reducing obstructive sleep apnea.
Jungquist, RN, PhD and her colleagues propose a seven-step framework "to translate evidence based guidelines and recommended best practices into an action-oriented stepwise process to recognize and systematically address the surveillance and prevention of opioid-induced unintended advancing sedation and respiratory depression
adverse events in hospital settings.
by eminent physicians and patient safety organisations1 are calling for routine continuous monitoring of respiratory rate in order to improve patient safety and help reduce the incidence of post-operative drug induced respiratory depression
, post-operative cognitive impairment (dementia) and cardiac arrests.
and death have occurred in children who had evidence of being ultra-rapid metabolizers of codeine (i.
Global Markets Direct's, 'Respiratory Depression
- Pipeline Review, H1 2012', provides an overview of the Respiratory Depression