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Caprion's involvement included the use of its CellCarta proteomics technology for the initial discovery of candidate biomarkers using a tissue-based proteomics approach on purified plasma membranes and secretory vesicles isolated from human lung cancer tissue specimens.
2+] is the primary intracellular signaling molecule controlling the fusion of secretory vesicles with the plasma membrane to release transmitters from neurons and hormones from endocrine cells (Martin, 2003).
Each granular gland consists of numerous alveoli or secretory vesicles that are surrounded by connective tissue (Hostetler & Cannon 1974; Cannon & Hostetler 1976; Alvarez et al.