obtained from cell lines or animal sources protect themselves and other cell types co-transplanted from destruction by the host's immune system without the need for chronic immunosuppressive drugs.
Sex cord-stromal tumors are derived from 2 types of somatic cells: the Leydig cells, and the Sertoli cells
This data suggests that Sertoli cells
may be useful in promoting functional recovery in earlier-stage Parkinson's patients, who are more likely to have sufficient residual dopamine-producing neurons to respond to neural regeneration therapy.
In the testis, the sertoli cells
induce differentiation of fetal leydig cells and act to maintain the gonocytes, and depending on species, the early spermatogonia .
Proliferation of Sertoli cells
during development of the human testis assessed by stereological methods.
Nonylphenol-induced oxidative stress and cytotoxicity in testicular sertoli cells
Differential effects of c-Src and c-Yes on the endocytic vesicle-mediated trafficking events at the Sertoli cell
blood-testis barrier: An in vitro study," American Journal of Physiology--Endocrinology and Metabolism 307(7): E553-E562.
A similar study on the rats indicates that the used fungicide MT caused dysfunction in the spermatogenesis and Sertoli cells
 which is necessary to the maturity of seminiferous tubules, throughout its role of nutrition of spermatozoa and this alters a dysfunction of the sperm count [31,32,33].
Further work on testicular pathology included the first English-language article on spermatocytic seminoma and description of the large cell calcifying Sertoli cell
A Sertoli cell
tumour in one testicle was producing female hormone that was reducing the size of the other.
proliferation induced by follicle-stimulating hormone (FSH) independently of luteinizing hormone activity: evidence from genetic models of isolated FSH action.
Possible hypotheses for this relationship include hypogonadotropic hyperestrogenic hypogonadism due to aromatization of steroids in estrogens in peripheral tissue; direct alterations of spermatogenesis and Sertoli cell
function; hip, abdominal, and scrotal fat-tissue accumulation, leading to increased scrotal temperature; and accumulation of toxins and liposoluble endocrine disruptors in fatty tissue.