Mutation

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Related to Silent mutation: genetic code, Nonsense mutation

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

References in periodicals archive ?
This study revealed that Cap+1 (A-C) is a silent mutation and it has only minimal effect on beta globin synthesis.
Of the four silent mutations 42 (ag), 138 (c [right arrow] t), 231 (c [right arrow] a) and 237 (g [right arrow] c) detected in this study, 237 (g [right arrow] c) is novel.
The mutation 2466 C [right arrow] T was a silent mutation.
Silent mutations such as the HFE variant T189C are usually considered insignificant, with the caveat that they could be involved with splice sites or DNA/protein binding sites.
All 39 W-Beijing isolates carrying the mutT2 polymorphism at codon 58 also displayed a concurrent silent mutation in codon 12 (Gly GGG to GGA Gly) of the ogt gene.
This 438G-->A sequence change is a silent mutation because both the wild-type ACA and the mutated ACG triplet encode for threonine at residue 146 of the GAMT peptide (T146T).
G3357A and T3394C are missense mutations (Met17Ileu and Tyr30His, respectively), and C3375A is a silent mutation.
In addition to the G238C transition discriminating for the TPMT*2 allele, further polymorphisms are known in exon 5, one silent mutation (C339T) and one mutation that produces a stop codon (G292T), which discriminates for the TPMT*3D allelic variant (Fig.
Minor] mutation site, the nucleotide sequence analysis revealed a silent mutation (G3315A) located 10 nucleotides upstream from the [Fin.
b) A silent mutation occurred at the last base of exon 4 and resulted in a 200-bp deletion of the mRNA (including one sequence primer site).
Some SNPs have a direct or even pathogenic impact on coding sequences, but many do not--either because they are outside of coding regions, or because they are silent mutations (ones that do not change amino-acid sequence) when in coding regions.