The expanding role of quantitative structure-activity relationships
(QSAR) in toxicology.
Assessment and use of quantitative structure-activity relationships
: a report from two ECET0C task forces, In: Quantitative Structure-Activity Relationships
in Environmental Sciences, VII (Chen F, Schuurmann G, eds).
Three-dimensional quantitative structure-activity relationships
for androgen receptor ligands.
By storing the results of several toxicology assessments in the database, dbZach facilitates comparisons of chemical mechanisms of action and supports functional toxicogenomic and chemoinformatic investigations of structure-activity relationships
2001, Development of quantitative structure-activity relationships
for the toxicity of aromatic compounds to Tetrahymena pyriformis: comparative assessment of the methodologies.
This presentation will describe structure-activity relationships
of Metabasis' lead inhibitor series and the glucose lowering activity of the lead compound, MB06322, in preclinical models of diabetes.
Immunosuppressive activities of potychlorinated dibenzofuran congeners: quantitative structure-activity relationships
and interactive effects.
They agreed, especially industry and regulatory authorities, that the workshop initiated great potential for the further development and use of predictive models, that is, quantitative structure-activity relationships
[Q)SARs], for chemicals management in a much broader scope than is currently the case.
SAR refers to structure-activity relationships
, where the term activity can refer to any property, or even to a collective score that represents many properties like our ADMET Risk score in ADMET Predictor.
Hydroxylated polychlorinated biphenyls (PCBs) as estrogens and antiestrogens: structure-activity relationships
Early studies in structure-activity relationships
helped pharmacology become a serious scientific discipline distinct from physiology.
The Classpharmer(TM) Suite enables generation of targeted compound screening lists and the automated extraction of structure-activity relationships
to predict both potency and toxicological properties of lead compounds.