Conclusion: These results indicate that TEN enhances the basic synaptic transmission
via stimulating presynaptic intracellular calcium.
Accumulation and extrusion of permeant Ca2+ chelators in attenuation of synaptic transmission
at hippocampal CA1 neurons.
Presynaptic calcium levels can regulate synaptic transmission
as well as neurotransmitter release into the synapse.
We highlighted the mechanism by which metals and their compounds interfere with the process of synaptic transmission
and synaptic plasticity," he said.
Adenosine is a neurotransmitter that normally inhibits synaptic transmission
and plasticity; that is, it induces sleepiness.
Acute alcohol exposure generally inhibits glutamatergic synaptic transmission
(Siggins et al.
Its goal is to advance understanding of the basic mechanisms of cell biology, synaptic transmission
,, cell motility, neural signaling and neurological disorders.
It's like when we first began to understand synaptic transmission
50 years ago.
One of the most consistent and intriguing findings associated with both dominant and recessive forms of Parkinson's, including those due to parkin mutations, have been defects in synaptic transmission
, possibly related to altered synaptic vesicle endocytosis, recycling or release," Dr.
Among the topics are multiple roles of voltage-gated sodium channels in the pathophysiology of pain, roles of unique mitochondrial ion channels in synaptic transmission
and programmed cell death, the effect of hypoxia-ischemia on voltage-dependent channels, the regulation of neuronal ion channels by G-protein-coupled receptors in sympathetic neurons, neuronal Kv7 potassium channels as emerging targets for treating pain, and high-throughput screening technologies in ion channel drug discovery.
Key words: excitatory neusotransmitters, glutamate, long-term potentiation, muscarinic, organic solvents, oxidative stress, reactive nitrogen species, retrograde messenger, synaptic transmission
Furthermore, an EphA4 knock-in mouse will be generated to study the effect of clustering during synaptic transmission
and on synapse stability in the hippocampus.