Moreover, the luciferase vectors were constructed from genomic DNA containing mutant TATA with the 5'-flanking region -2,657 to +39 (p[beta]CE1mTATA) and -2,657 to +2,450 containing intron 1 (p[beta]CE2mTATA) to validate the necessity of the normal or mutant TATA box
in the promoter for expression of the [beta]-casein gene.
Hoechst 33342 induces apoptosis, inhibitstopoisomerase I and alters TATA box
binding protein/DNA complexes in HT-144 melanoma cells.
PCR primers were designed from the GenBank reference sequence for UGT1A1 to amplify a small (59-bp) amplicon containing the UGT1A1 promoter TATA box
Several studies have identified elements of the CYP1A1 regulatory region that are involved in AhR-mediated transcriptional activation of this gene, including a TATA box
, an NF-1 binding site, and eight AhR response elements (AhREs) (1,15,17).
The main cause of GS in all studied populations is a TA insertion in the repetitive TATA box
of the gene promoter (3-6), which usually consists of 6 repeats.