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inhibitor
(redirected from Topoisomerase I)

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See: deterrent


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8), and more recently, the need for such an enzyme has been reiterated by those examining the actions of topoisomerase I inhibitors (9, 10).
The researchers looked at how cancer cells reacted when given PARP inhibitors alongside a type of chemotherapy called topoisomerase I poisons.
Topoisomerase inhibitors that inhibit either topoisomerase I or II are used to treat a number of different tumor types: camptothecins (topoisomerase I inhibitors) for colorectal cancer; anthracyclines (topoisomerase II inhibitors) for breast, ovarian, bladder cancer and Non Hodgkin's Lymphoma; etoposide (topoisomerase II inhibitor) for lung cancer.
 
 
 
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