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Related to Transfusion-related immunomodulation: TRALI, transfusion reaction, PubMed, Transfusion related acute lung injury
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Key words: Blood transfusions, transfusion-related immunomodulation, leukodepletion, infections, mortality, cardiac surgery
Chapter 10, the only chapter to specifically address "Deleterious Clinical Effects" of transfusion, limits the discussion to a very controversial topic, that of transfusion-associated immunomodulation (generally referred to in the text and other publications as transfusion-related immunomodulation [TRIM]).
The authors point out that leukocyte reduction may reduce the risk of transfusion-related immunomodulation (TRIM), depression of the immune system which may predispose a patient to post-operative infection.

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