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Accuracy of antitissue transglutaminase IgA antibody in the diagnosis of paediatric celiac disease.
The immune response in celiac disease involves the production of antibodies against the intestinal enzyme tissue transglutaminase.
Conclusion: This study showed a positive correlation between the tissue transglutaminase titre and the degree of duodenal damage (Marsh IIIC) in patients with coeliac disease.
39) The tissue transglutaminase (TTG) antibody test is recommended for diagnosis.
Serum transglutaminase correlates with endoscopic and histopathologic grading in patients with ulcerative colitis.
Electrochemical immunosensor for anti-tissue transglutaminase antibodies based on the in situ detection of quantum dots.
Screening of tissue transglutaminase antibody in healthy blood donors for celiac disease screening in the Turkish population.
Fortunately, the identification of anti-endomysium immunoglobulin A (EMA-IgA) and anti-tissue transglutaminase immunoglobulin A (tTG-IgA) as markers for celiac disease has provided serological testing of high sensitivity (greater than 90%) and specificity (greater than 95%) for initial screening of children and youth.
Key words: Celiac Disease, Irritable Bowel Syndrome, Tissue transglutaminase IgA antibody, Puerto Rico
Symptoms of gluten sensitivity often mimic those of celiac disease or IBS, though with gluten sensitivity there is no damage to the small intestine, nor do patients develop tissue transglutaminase antibodies that are found in celiac disease.