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Urtica fissa was collected in July, 2005 at Anshun mountains in Guizhou Province of China, and identified by Professor Liu Cun-sheng in Beijing University of Chinese Traditional Medicine.
Urtica fissa roots and stems (50 kg) were pre-extracted with 4001 95% ethanol to remove color materials.
Fifty kg of roots and stems of Urtica fissa were extracted with hot water and subjected to ultrafiltration to obtain 402 g of crude polysaccharide fraction.
Evaluation of a test and its application to Urtica dioica root extracts.
Stimulation of lymphocyte proliferation and inhibition of nitric oxide production by aqueous Urtica dioica extract.
The presence of a relatively high concentration of flavonoids and caffeic acid derivatives enriched in the lipophilic fraction of the Urtica herb, suggest mainly anti-inflammatory, antioxidant and analgesic activities as assessed in a series of pharmacaological in vitro and animal studies, some of them also against the synthetic Diclofenac[R].
As the toxicology of Urtica herbal extract is concerned, it has to be carfully proven, whether in the allergic skin side-effects observed in some patients after administration of the Urtica extract, the caffeoylesters are involved.
Key words: biotransformation enzymes, antioxidant enzymes, lipid peroxidation, sulfhydryl groups, lactate dehydrogenase, Urtica dioica L.
Urtica dioica plants were collected from the Samsun, Turkey, in July-August (2001), during the early hours of the day.
The combination of sabal and urtica extract shows clear advantages regarding the patients' 'subjective' apperception and evaluation of LUTS as compared to placebo according to the I-PSS.
Sivkov A, Kohler S, Engelmann U, Medvedev A, Lopatkin N (2001) Long-term efficacy and safety of a combination of sabal and urtica extracts in LUTS--a placebo-controlled, double-blind, multicenter trial.
Urtica dioica is recommended at a dose of 20 drops in a little water twice a day before meals.