The gonadotropins FSH and LH bind to specific G-protein-coupled receptor sites to stimulate adenylate cyclase and the accumulation of cAMP, which activates
enzymes involved in steroidogenesis (Hsueh et al.
Further investigation revealed that the fly protein recognizes a separate insect protein produced during a fungal infection and in turn, activates
the fly's immune response.
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Rather than activate
the normally silent gene, the mutation silenced the normally active gene, thus thwarting the production of the corresponding proteins in the embryo, Li says.
Before they reinfuse the white blood cell fraction, they expose it to ultraviolet light, which activates
the psoralen for a few thousandths of a second.