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| Cadmium induces apoptosis in anterior pituitary cells that can be reversed by treatment with antioxidants. Specifically, in response to stress, the hypothalamus (1) stimulates autonomic centers within the medulla activating the sympathetic nervous system, (2) releases corticotropin-releasing factor (CRF) activating the anterior pituitary gland, and (3) stimulates the posterior pituitary gland. When the anterior pituitary gland is involved, the production of growth hormone may drop. |
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