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The antigen-binding site is formed where a heavy chain variable domain (VH) and a light chain variable domain (VL) come close together.
2], and Fab'), investigators now have an expanding repertoire of antibody forms with variable numbers of antigen-binding sites and with different molecular sizes and shapes.
The three-dimensional structure of HLA-B27 has a unique stereospecific antigen-binding site.
 
 
 
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