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Related to antigen-binding site: variable region, Surface immunoglobulin
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peptides binding to the antigen-binding site, and to compare the structures of these with that of the antigen (21,24-26).
This tested whether the peptide was truly binding at or very close to the antigen-binding site on the ER 1D5 mAb.
When two polypeptide chains, VHA-VLB and VHB-VLA, linked by the short linkers are expressed in the same cells, dual-functional antigen-binding sites are formed by crossover pairing of the variable light-chains and heavy-chains.

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