compound

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Related to antisense compound: Antisense therapy, antisense DNA

compound

adjective aggregate, aggregated, associated, blended, combined, commixed, complex, complicated, composite, conglomerate, congregated, conjoint, conjugate, connected, convoluted, elaborate, embodied, fused, hybridized, incorporated, infused, inseparable, integrated, interlaced, intermingled, interwoven, intricate, involved, manifold, merged, mingled, mixed, mosaic, multifarious, multiform, multiple, multiplex, solid, tied, united, varied, variegated, woven
Associated concepts: compound a crime, compound interrst, compound larceny, compounding a felony
Foreign phrases: Aestimatid praeteriti delicti ex postremo facto nunquam crescit.The weight of an offense committed in the past is never increased by a subsequent fact.

compound

verb accrue, add to, advance, aggravate, amount, amplificare, annex, append, augere, be augmented, be numerous, become greater, become larger, branch out, build up, burgeon, connribute to, develop, dilatare, dilate, distend, elaborate, enhance, enlarge, enrich, exacerbate, exaggerate, exalt, expand, fill in, fill out, fortify, further, gain ground, gain strength, get ahead, give strength to, glorify, greaten, grow larger, heighten, increase, increase the numbers, inflate, lend force to, lengthen, magnify, make greater, make larger, multiply, open out, parlay, pile up, prolong, protract, raise, refine, reinforce, restrengthen, spread out, strengthen, subjoin, superadd, supplement, widen
Associated concepts: compounding a crime, compounding a debt, compounding a felony, compounding penalty
Foreign phrases: Aestimatio praeteriti delicti ex postremo facto nunquam crescit.The weight of a past crime is never increased by a subsequent fact.
See also: adhere, close, coalescence, collective, combination, combine, commingle, complex, composite, confines, conglomerate, conjoin, consolidate, desegregate, development, include, incorporate, incorporation, join, make, melange, merge, solution, substance, unite

compound

to agree not to prosecute or proceed in return for a consideration.
References in periodicals archive ?
The retention of this novel transcript demonstrated that the antisense compound was inhibiting splicing, the process by which the intervening sequences are normally removed from the mRNA.
Early research by Isis indicated that an antisense compound would prove effective against CMV if it homed in on one of the messenger RNAs that help produce the series of proteins CMV needs for replication.
Patent 5,506,212, "Oligonucleotides Having Substantially Chirally Pure Phosphorothioate Linkages," covers chiral forms of Isis-owned antisense compounds directed toward human papilloma virus.
He hopes to begin human clinical trials of antisense compounds within two years.
These novel compounds are based on the company's proprietary chemistries which enable Isis to design novel antisense compounds with a wide range of attractive drug properties and represent significantly enhanced therapeutic potential over first generation compounds.
Antisense compounds with these backbones have greater binding affinity in vitro and, as a result, have the potential for greater potency than first generation antisense compounds.
5 /PRNewswire/ -- Isis Pharmaceuticals (Nasdaq: ISIP) announced it has been issued a United States Patent covering "oligonucleosides," novel antisense compounds that have chemically modified backbones in which phosphate linkages are replaced by non-phosphate linkages.
Isis believes that ISIS 2922 is the first antisense compound to show clinical activity in humans.
The compound described in the Journal of Immunology study is a mouse equivalent of ISIS 2302, an antisense compound that Isis is developing to treat a variety of human inflammatory diseases.
The Isis ICAM-1 antisense compound was demonstrated to work synergistically with several other types of immunosuppressive agents.
The use of two different, or chimeric, chemistries in designing an antisense compound resulted in an increased affinity of the compound to bind with its target gene -- Ha-ras.
If permission is granted to commence human clinical trials, ISIS 2105 will be the first antisense compound to be injected into humans.