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The upper outlier in group 2B was a patient with tuberculous meningitis and strongly impaired blood-CSF barrier function ([Q.
Blood-CSF barrier permeability abnormalities and quantitative measurement of intrathecal IgG synthesis assessed by the albumin ratio, the IgG/albumin index, the Tourtelotte index, the Schuller index, and the Reiber index.
The CSF protein concentration depends on the serum protein concentration and on the permeability of the blood-CSF barrier.
The goal of this Program Announcement with set-aside funds (PAS) is to invite applications for studying the neurobiological and cerebrovascular mechanisms through which the neuroprotective blood-brain and blood-csf barriers function in the healthy and diseased adult, aged and pediatric brain.