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Related to cafe au lait spots: neurofibromatosis
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Patients may have skin stigmata, usually cafe au lait spots, but these may be subtle.
She was known to have von Recklinghausen's disease with the typical cafe au lait spots.
A special type of polyostotic fibrous dysplasia is McCune-Albright syndrome, which is associated with precocious sexual development and cafe au lait spots on the skin.