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Related to calcified: Calcified fetus
See: ossified
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COAST builds on CSI's ORBIT II study, reportedly the first trial designed to treat patients with severely calcified lesions who typically are excluded from all major trials, but commonly seen in the real world.
The Diamondback 360 Orbital Atherectomy System (OAS) catheter was used to treat severely calcified lesions prior to stent placement.
No association between any measure of calcified plaque and calcium intake from diet or supplements was observed, nor was increased calcium intake associated with a greater risk of all-cause mortality over follow-up.
However, computed tomographic (CT) angiography demonstrated that the styloid processes were elongated and the stylohyoid ligaments were calcified bilaterally (figure 1).
Focus: The ORBIT I trial was conducted to evaluate the safety and performance of the Diamondback 360[R] Orbital Atherectomy System (OAS) for the treatment of calcified coronary lesions.
Patients had calcified above-the-knee lesions greater than 70 percent and were equally randomized to PTA alone versus a therapy with the Diamondback[TM] Orbital Atherectomy System (Diamondback) with adjunctive PTA.
The RockHawk device, currently under development, is a specialized version of FoxHollow's SilverHawk(R) Plaque Excision System that is optimized for the treatment of calcified lesions in the peripheral arteries.
These data show that CSI's Diamondback Orbital Atherectomy System can be safely used for treating calcified lesions in the OBL setting, with the positive patient outcomes consistent with those seen in the hospital environment.
Patients had calcified above-the-knee lesions greater than or equal to 70 percent, and were equally randomized to PTA alone versus therapy with the Diamondback Orbital Atherectomy System.
In this article, we describe a case of a malignant change in a calcified pleomorphic adenoma of the deep parotid lobe that manifested as facial pain.
It demonstrated that plaque excision with Covidien's TurboHawk[TM] device utilizing distal embolic protection with the SpiderFX can be used safely and effectively in patients who have severely calcified superficial femoral artery and popliteal artery lesions, including those with single vessel runoff.