Biomarker data showed that CYC202 is inducing cancer cell
suicide or apoptosis in 54% (14/26 analyzed) of patients with solid tumors.
In this study, we used a prostate cancer cell
model in which an immortalized, nontumorigenic human prostate epithelial cell line (RWPE-1) had been malignantly transformed by chronic low-level arsenic to help determine whether arsenic affects prostate tumor progression.
The Cancer Survival Protein modulation platform has generated a clinical-stage product designed to inhibit a molecule known as c-Met, which plays multiple roles in cancer cell
growth, survival, invasion, angiogenesis and metastasis.
Synthetic isomeric preparations of the compound stimulated breast cancer cell
proliferation and blocked estrous cyclicity in female rats but were devoid of biologic effects on male sexual behavior.
The antiproliferative effects were reversed by the addition of palmitate, the precursor for the majority of nonessential fatty acids, which cancer cells
use primarily for energy and growth.
turn on genes that allow cancer cells
But the minute size of cancer cells
can make tests deceiving.
ISLAMABAD -- A new research has explained how studying the diversity of cancer cells
could help turn off mutations in cancer cells
and strip their adaptability to drugs.
If any remaining cancer cells
had continued to grow normally, the disease should have returned in weeks or months.
Results that demonstrate that, upon entering a cancer cell
, a TAP compound is rapidly activated - causing cell-cycle arrest - and this activation involves lysosomal processing (abstract #1175);
These data suggest that the observed effect of GRN163L on lung cancer cells
may be mediated in part by the altered cell adhesion induced by this novel cancer therapeutic agent, and that GRN163L may have additional benefit in prevention of metastasis.
that have traveled to new locations in the body and grown there cause most cancer pain and cancer-related deaths.