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Related to capsular space: Bowman's capsule
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The expansion in capsular space is probably caused by enhanced angiotensin II level leading to increased intraglomerular pressure and filtration rate (Wolf et al.
EGb 761 showed some beneficial effects in STZ diabetic rat kidneys: glomerular hypertrophy, dilation of the capsular space, thickening of Bowman's capsule BM, ultrastructural lesions on capillaries and podocytes were reduced, increase in collagen fibers of type I, III, and VI in the tubular interstitium was diminished, increased SOD activity was equalized.