Hains BC, Chastain KM, Everhart AW, McAdoo DJ, Hulsebosch CE, "Transplants of Adrenal Medullary Chromaffin Cells
Reduce Fore Limb and Hind Limb Allodynia in a Rodent Model of Chronic Central Pain after Spinal Cord Hemisection Injury", Exp.
One-year chromaffin cell
allograft survival in cancer patients with chronic pain: Morphological and functional evidence.
were washed three times before experiments.
Pheochromocytoma (PCC) is a catecholamine-secreting tumour from chromaffin cells
of the embryonic neural crest.
True (A) or false (B)--click on the correct answer: approximately 85% of phaeochromocytomas arise from chromaffin cells
in the adrenal medulla.
Voltage-sensitive calcium flux into bovine chromaffin cells
occurs through dihydropyridine-sensitive and dihydropyridine- and omega-conotoxin-insensitive pathways.
Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells
These distinct patterns of gene expression indicate different pathways of tumorigenesis, possibly involving development of tumors from different populations of chromaffin cells
with different susceptibilities to the effects of a particular mutation.
Malignancy is normally determined by evidence of infiltration of surrounding tissues or by the spread of disease to distant sites, particularly those where chromaffin cells
are not usually found (eg, lymph nodes, bone).
Pheochromocytoma arises from chromaffin cells
and usually develops in the adrenal medulla.
In summary, it is essential to be aware that paragangliomas may arise from the embryonic chromaffin cells
that may have accompanied the testis; nevertheless, it is important to rule out a metastasis from other sites.
Further support for these conclusions is the result of transplant studies in which adrenal chromaffin cells
were used to prevent and/or reverse the expression of injury-induced pain behaviors [50-52].