more unprocessed precursor compared to biosynthetic cleavage products
in severe heart failure.
When reexamined, three of the samples did contain weak cleavage products
corresponding to the expected fragment sizes when compared with cDNA sequence data but were not registered as mutated during the blind phase of the study.
In samples with the T833C mutation, the fluorescent cleavage product
is from the coding strand.
Quantitative analysis of the cleavage products
generated during the processing of amyloid precursor protein is critical to the understanding of the pathogenesis of Alzheimer's disease," said Joe Bertelsen, Neuroscience Product Manager, Signet Laboratories, Inc.
sz]-Amyloid (A[sz]) peptides are generated as cleavage products
39 to 43 amino acids in length from the membrane protein, Amyloid Precursor Protein (APP) by two proteases, ?
Aromatic rings are dihydroxylated and then ring cleavage occurs and ultimately cleavage products
are metabolized [1,4]
were recovered after SDS/Proteinase K treatment.
Another method that combines immunoaffinity chromatography with specific antibodies for cleavage products
has been successful in detecting BoNT B in some foods at lower detection limits than the mouse bioassay (10).
Identical ring cleavage products
during anaerobic degradation of naphthalene, 2-methylnaphthalene, and tetralin indicate a new metabolic pathway, Appl Environ Microbiol 68(2):852-858.
The reaction is composed of 3 steps: binding of the ribozyme to the target, cleavage of the target, and release of the cleavage products
The oxidation results in two classes of compounds: [alpha]-hydroxylation products and ring cleavage products