clone

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clone

noun a carbon copy created by genetic engiieering, a copy created by genetic engineering, a double created by genetic engineering, a facsimile created through genetic engineering, an exact copy created through genetic engineering, duplication created by geeetic engineering, production of a copy, production of a copy through genetic engineering, production of multiple identical copies, propagation asexually, propagation from a clone cell, replication created by genetic engineering, replication through genetic engineering, reproduction asexually
Associated concepts: bioethics, computer clone, embryo splitting, human clone
References in periodicals archive ?
Profiling clonality and progression in multiple premalignant and malignant oral lesions identifies a subgroup of cases with a distinct presentation of squamous cell carcinoma.
TCRp clonality improves diagnostic yield of TCRy clonality in refractory celiac disease.
To evaluate molecular clonality, three slices of 10p FFPE tissue were used for extraction of DNA according to the protocol previously described by Maria et al [13].
To examine the degree of clonality within sampling locations, repeated genotypes were documented and inbreeding coefficients ([F.
As a measure of degree of clonality, we calculated the genotype discovery rate between genotypes (G) and number of individuals sampled (N) (G/N) (Ellstrand & Rose, 1987; Silvertown, 2008) and the unbiased probability of identity P(ID), which corrects for deviations from HW and LD (Waits et al.
T-cell clonality studies were performed in the peripheral blood and revealed a genetic rearrangement pat-tern of the beta chain T-cell receptor (TCR-beta) and abnormal T clone in seven metaphases with loss of Y chromosome.
They cover basic principles of electrophoresis, protein constituents of serum, determining immunoglobulin clonality and quantifying specific serum proteins, monoclonal gammopathies, urine protein electrophoresis, and a clinical approach.
At the end, an open lung biopsy with thoracotomy for interstitial lung disease and thymectomy were performed, and the pathologic diagnosis was as micronoduler type thymoma, surrounded by monoclonal B cell proliferation approved by molecular clonality studies and also amyloid accumulation in the lung, which was shown to be AL type of amyloid by mass spectrometry (Figure 2).
Both the polymerase chain reaction (PCR) and fluorescence in situ hybridisation (FISH) identify tiny regions of DNA of interest to establish clonality for confirmation of malignancy in a lymphoid population, or to look for characteristic translocations, deletions and gene amplifications in the DNA which are specific for certain subtypes of lymphomas.