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In conclusion, PRES should be considered in the differential diagnosis of acute encephalopathy in patients who present with new-onset seizures, systemic hypertension, and clouding of consciousness.
Some patients (especially the ones with microadenomas) may present with an acute clinical picture characterized with headache, vomiting, loss of vision, ophthalmoplegia and clouding of consciousness due to pituitary apoplexy which is a rare condition (4).
The second patient who was aged 18 years and addicted to synthetic cannabinoid 'bonzai' was brought to our emergency department by his friends because of clouding of consciousness.