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Related to collagen disease: Scleroderma, Connective tissue disorder
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Yoshihiro Hirata, a Japanese chiropractor, who suffered from painful collagen disease, founded the Phi-Ten Co.
6 Lupus, one of the family of autoimmune collagen diseases where the body attacks its own collagen wherever it is.
In one Japanese study of 57 patients with rheumatoid arthritis, 47 with systemic sclerosis, 21 with polymyositis/derrnatomyositis, and 18 with systemic lupus erythematosus, KL-6 was found to be a useful marker for diagnosis and evaluation of interstitial pneumonia activity associated with collagen diseases.